Utilities and Design Aids for Up-and-Down Dose-Finding Studies

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Documentation for package ‘upndown’ version 0.3.0

Help Pages

bcd Up-and-Down Design Rules for use in Dose-Finding Simulator
bcdmat Transition Probability Matrices for Up-and-Down Designs
bcoin Up-and-Down Target Calculation and Design Guidance
checkCDF Data Validation Utilities for 'upndown'
checkDose Data Validation Utilities for 'upndown'
checkNatural Data Validation Utilities for 'upndown'
checkResponse Data Validation Utilities for 'upndown'
checkTarget Data Validation Utilities for 'upndown'
classicmat Transition Probability Matrices for Up-and-Down Designs
cumulvec Key Probability Vectors of Up-and-Down Designs
currentvec Key Probability Vectors of Up-and-Down Designs
dfboot Generic percentile dose-response / dose-finding bootstrap routine
dfsim Generalized Dose-Finding Ensemble Simulator
dixonmood Original Dixon and Mood (1948) point estimate
drplot Visualizing the dose-response summary of an up-and-down experiment
dynamean Up-and-Down target-dose averaging estimate, with dynamic cutoff-point
g2targ Up-and-Down Target Calculation and Design Guidance
groupUD Up-and-Down Design Rules for use in Dose-Finding Simulator
gtargOptions Up-and-Down Target Calculation and Design Guidance
gudmat Transition Probability Matrices for Up-and-Down Designs
k2targ Up-and-Down Target Calculation and Design Guidance
kmatFull Transition Probability Matrices for Up-and-Down Designs
kmatMarg Transition Probability Matrices for Up-and-Down Designs
krow Up-and-Down Design Rules for use in Dose-Finding Simulator
ktargOptions Up-and-Down Target Calculation and Design Guidance
pivec Key Probability Vectors of Up-and-Down Designs
reversals Reversal-anchored averaging estimators for Up-and-Down
reversmean Reversal-anchored averaging estimators for Up-and-Down
udest Centered-Isotonic-Regression (CIR) Estimate for the Up-and-Down Target Dose
udplot Visualizing the time series of an up-and-down experiment
validUDinput Data Validation Utilities for 'upndown'