Empirical Bayes Methods for Pharmacovigilance


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Documentation for package ‘pvEBayes’ version 0.1.1

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AIC.pvEBayes Obtain Akaike Information Criterion (AIC) for a pvEBayes object
BIC.pvEBayes Obtain Bayesian Information Criterion (BIC) for a pvEBayes object
estimate_null_expected_count Estimate expected null baseline count based on reference row and column
extract_all_fitted_models Extract all fitted models from a tuned pvEBayes Object
eyeplot_pvEBayes Generate an eyeplot showing the distribution of posterior draws for selected drugs and adverse events
gbca2025 FDA GBCA dataset with 1328 adverse events
gbca2025_69 FDA GBCA dataset with 69 adverse events
generate_contin_table Generate random contingency tables based on a reference table embedded signals,and possibly with zero inflation
heatmap_pvEBayes Generate a heatmap plot visualizing posterior probabilities for selected drugs and adverse events
logLik.pvEBayes Extract log marginal likelihood for a pvEBayes object
plot.pvEBayes Plotting method for a pvEBayes object
posterior_draws Generate posterior draws for each AE-drug combination
print.pvEBayes Print method for a pvEBayes object
pvEBayes Fit a general-gamma, GPS, K-gamma, KM or efron model for a contingency table.
pvEBayes_tune Select hyperparameter and obtain the optimal general-gamma or efron model based on AIC and BIC
statin2025 FDA statin dataset with 5119 adverse events
statin2025_44 FDA statin dataset with 44 adverse events
statin42 FDA statin dataset with 42 adverse events
summary.pvEBayes Summary method for a pvEBayes object